Description

Carbocyclic 3'-Oxa-2',3'-Dideoxy-7-Deazaguanosine is a specialized nucleoside analog with a modified sugar and base structure, designed for advanced biochemical research and pharmaceutical development. This compound is valued for its role as a key intermediate and building block in the synthesis of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular enzymes. It is essential for researchers and manufacturers in the fields of medicinal chemistry, nucleotide therapeutics, and molecular biology who require high-purity, structurally defined compounds for their critical work.

Application

• Medicinal Chemistry Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Antiviral Research: Used in the development of compounds targeting viral polymerases, such as those from hepatitis and herpes virus families.
• Enzyme Inhibition Studies: Serves as a substrate or inhibitor in biochemical assays to study the function of nucleoside-processing enzymes.
• Nucleotide Analog Development: A precursor for creating modified nucleotides used in probing nucleic acid structure and function.
• Pharmaceutical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in API manufacturing.
• Bioconjugation and Probe Synthesis: Utilized in the creation of labeled nucleotides for diagnostic and imaging applications.

Basic Information

Product Name	Carbocyclic 3'-Oxa-2',3'-Dideoxy-7-Deazaguanosine
CAS No.	149519-40-4
Molecular Formula	C₁₁H₁₃N₅O₃
Molecular Weight	263.25 g/mol
Synonyms	7-Deaza-2',3'-dideoxy-3'-oxaguanosine, carbocyclic analog; Carbocyclic 3'-oxa-2',3'-dideoxyguanosine, 7-deaza-; 9-[(1S,4R)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 2-Amino-9-[(1S,4R)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-ol; c-OddG; Carbocyclic oxetanoicin G
EINECS	Contact for details

Quality Control

Our Carbocyclic 3'-Oxa-2',3'-Dideoxy-7-Deazaguanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.