Description

Adenosine, 2-Chloro-n-Cyclopropyl- is a chemically modified nucleoside analog, specifically engineered for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a versatile building block for creating novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of nucleoside-based prodrugs and targeted molecular probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel adenosine receptor agonists and antagonists for neurological and cardiovascular research.
• Antiviral Drug Development: Building block for prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Used in the development of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool: Acts as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and signaling pathways.
• Prodrug Synthesis: Modified to enhance bioavailability and target specificity in drug delivery systems.
• Labeled Compound Synthesis: Serves as a starting material for the preparation of isotopically labeled (e.g., C13, N15) analogs for pharmacokinetic studies.

Basic Information

Product Name	Adenosine, 2-Chloro-n-Cyclopropyl-
CAS No.	149007-83-0
Molecular Formula	C13H16ClN5O4
Molecular Weight	341.75 g/mol
Synonyms	2-Chloro-N-cyclopropyladenosine; 2-Chloro-cyclopropyladenosine; 2-Cl-cPr-Ado; N-Cyclopropyl-2-chloroadenosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-chloro-6-(cyclopropylamino)purine; 2-Chloro-N6-cyclopropyl-9-β-D-ribofuranosyladenine
EINECS	Contact for details

Quality Control

Our Adenosine, 2-Chloro-n-Cyclopropyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.