Description

5-Thiazolecarbonyl Chloride, 2-Chloro- (9Ci) is a high-purity, reactive organosulfur intermediate essential for advanced chemical synthesis. Its value lies in its role as a key building block for constructing complex heterocyclic frameworks, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is critically needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of thiazole-containing drug candidates, including potential antiviral, antibacterial, and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the thiazole moiety for biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials with specific electronic or thermal properties.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal catalysis or as a scaffold for organocatalysts in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Thiazolecarbonyl Chloride, 2-Chloro- (9Ci)
CAS No.	148637-74-5
Molecular Formula	C4HCl2NOS
Molecular Weight	182.02 g/mol
Synonyms	2-Chloro-1,3-thiazole-5-carbonyl chloride; 2-Chlorothiazole-5-carbonyl chloride; 2-Chloro-5-thiazolecarbonyl chloride; 2-Chloro-1,3-thiazole-5-carboxylic acid chloride; 2-Chlorothiazole-5-carboxylic acid chloride; 5-Carboxy-2-chlorothiazole chloride; (2-Chloro-1,3-thiazol-5-yl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Thiazolecarbonyl Chloride, 2-Chloro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and reactive acid chloride nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Keep away from moisture, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.