Description

Ripisartan CAS NO 148504-51-2 is a high-purity active pharmaceutical ingredient (API) belonging to the angiotensin II receptor blocker (ARB) class. This compound is critical for the research and development of novel cardiovascular therapeutics targeting hypertension and related conditions. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in drug discovery and formulation studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced ARB drug candidates.
• Research & Development: Used in preclinical and clinical studies to investigate mechanisms of action and therapeutic efficacy for cardiovascular diseases.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Formulation Development: Integral to the development of solid dosage forms such as tablets and capsules in pharmaceutical manufacturing.
• Biochemical Research: Utilized in studies exploring the renin-angiotensin system and its role in blood pressure regulation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and commercial production.

Basic Information

Product Name	Ripisartan
CAS No.	148504-51-2
Molecular Formula	C25H24N6O3
Molecular Weight	456.50 g/mol
Synonyms	Ripisartan; BIBR-277; 2-Butyl-5-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid; BIBR 277; BIBR277; UNII-6KVL22J8Q5
EINECS	Contact for details

Quality Control

Our Ripisartan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.