Description

6-Amino-9-[2-Deoxy-β-D-Ribofuranosyl]-9H-Purine is a high-purity nucleoside derivative, a key building block in oligonucleotide synthesis and pharmaceutical research. Its precise chemical structure makes it an essential intermediate for the development of novel therapeutics, including antiviral and anticancer agents. This compound is critical for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleic acids and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside-based antiviral and anticancer drugs.
• Oligonucleotide Synthesis: Used as a modified nucleoside phosphoramidite building block for antisense oligonucleotides and siRNA.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to DNA/RNA metabolism and repair.
• Proteomics & Diagnostics: Employed in the development of diagnostic probes and labeling reagents for nucleic acid detection.
• Academic Research: Fundamental material for studying nucleic acid chemistry, structure-activity relationships, and drug discovery.
• Fine Chemical Synthesis: Intermediate for the custom synthesis of more complex, target-specific nucleoside analogs.

Basic Information

Product Name	6-Amino-9-[2-Deoxy-β-D-Ribofuranosyl]-9H-Purine
CAS No.	148171-35-1
Molecular Formula	C₁₀H₁₃N₅O₃
Molecular Weight	251.24 g/mol
Synonyms	2'-Deoxyadenosine, N6-Amino derivative; 6-Amino-9-(2-deoxy-β-D-ribofuranosyl)-9H-purine; 2'-Deoxy-6-aminopurine riboside; 6-Amino-2'-deoxyadenosine; 6-Aminopurine-2'-deoxyriboside; dA(N6); 2'-Deoxyisoguanosine; 6-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-9H-purine
EINECS	Contact for details

Quality Control

Our 6-Amino-9-[2-Deoxy-β-D-Ribofuranosyl]-9H-Purine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. We provide Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research and cGMP-grade standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep the container sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.