Description

24-Nor-9,11-Seco-11-Acetoxy-3,6-Dihydroxycholest-7,22-Dien-9-One CAS NO 147879-65-0 is a high-purity, semi-synthetic steroid derivative with a complex, modified cholestane backbone. This compound is of significant value as a critical pharmaceutical intermediate and a versatile reference standard for research and development. It is primarily needed by pharmaceutical manufacturers and biochemical research laboratories engaged in the synthesis of novel therapeutic agents and advanced metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference compound or substrate in studies of steroid metabolism, enzyme inhibition, and receptor binding assays.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories (HPLC, LC-MS).
• Academic Research: Facilitates investigations in organic chemistry, medicinal chemistry, and pharmacology for developing new synthetic pathways.
• Process Development: Employed in scaling up and optimizing synthetic routes for steroid derivatives in pilot plants and manufacturing settings.

Basic Information

Product Name	24-Nor-9,11-Seco-11-Acetoxy-3,6-Dihydroxycholest-7,22-Dien-9-One
CAS No.	147879-65-0
Molecular Formula	C₂₈H₄₂O₅
Molecular Weight	458.64 g/mol
Synonyms	11-Acetoxy-24-nor-9,11-seco-3,6-dihydroxycholesta-7,22-dien-9-one; 24-Norcholesta-7,22-diene-3,6,11-triol, 11-acetate, 9,11-seco-9-oxo-; 9,11-Secocholest-7,22-dien-9-one, 24-nor-11-(acetyloxy)-3,6-dihydroxy-; (3β,5ξ,6β,22E)-11-(Acetyloxy)-24-nor-9,11-secocholesta-7,22-diene-3,6,9-triol; 24-Nor-9,11-seco-11-acetoxy-3,6-dihydroxycholest-7,22-dien-9-one; 147879-65-0; Steroid derivative 147879-65-0.
EINECS	Contact for details

Quality Control

Our 24-Nor-9,11-Seco-11-Acetoxy-3,6-Dihydroxycholest-7,22-Dien-9-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.