Description

1,3-Oxathiolane-2-Carbonyl Chloride, 5-Oxo- (9Ci) is a highly reactive and versatile chemical building block, specifically an acid chloride derivative of a functionalized oxathiolane. Its core value proposition lies in its ability to act as a key intermediate for introducing the 5-oxo-1,3-oxathiolane moiety into more complex molecular architectures, enabling advanced synthesis in specialized chemical fields. This compound is essential for research chemists and process development scientists working in pharmaceutical development, particularly in medicinal chemistry for creating novel therapeutic candidates, and in advanced material science.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and pharmacokinetic properties.
• Heterocyclic Compound Synthesis: A key building block for constructing complex sulfur- and oxygen-containing heterocycles, which are prevalent in many bioactive molecules.
• Agrochemical Development: Employed in the research and synthesis of new generation pesticides and herbicides with unique modes of action.
• Material Science Precursor: Can be utilized in the development of specialized polymers or functional materials with specific chemical or physical properties.
• Chemical Biology Probes: Acts as a reagent for modifying biomolecules or creating chemical probes to study biological processes.

Basic Information

Item	Details
Product Name	1,3-Oxathiolane-2-Carbonyl Chloride, 5-Oxo- (9Ci)
CAS No.	147027-07-4
Molecular Formula	C4H3ClO3S
Molecular Weight	166.58 g/mol
Synonyms	5-Oxo-1,3-oxathiolane-2-carbonyl chloride; 2-Chlorocarbonyl-1,3-oxathiolan-5-one; 1,3-Oxathiolane-2-carbonyl chloride, 5-oxo-; 5-Oxo-1,3-oxathiolane-2-carboxylic acid chloride; Oxathiolane carbonyl chloride derivative; Thiolane carbonyl chloride, oxo- derivative
EINECS	Contact for details

Quality Control

Our production of 1,3-Oxathiolane-2-Carbonyl Chloride, 5-Oxo- (9Ci) adheres to stringent quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.