Description

Cyclazosin Hydrochloride is a potent and selective α-1B adrenergic receptor antagonist. This compound is of significant value in pharmacological research and development, particularly for studying cardiovascular and urogenital systems. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and contract research organizations (CROs) focused on receptor pharmacology and drug discovery.

Application

• Pharmacological Research: Used as a reference standard and tool compound for investigating the physiological role of α-1B adrenoceptors.
• Drug Discovery Programs: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel cardiovascular and urogenital therapeutics.
• Biochemical Assays: Employed in in vitro binding and functional assays to characterize receptor-ligand interactions and screen for new compounds.
• Academic Studies: Utilized in university and institutional research to explore autonomic nervous system regulation and related disease models.
• Preclinical Development: Applied in animal studies to evaluate the efficacy and mechanism of action of potential new drugs targeting adrenergic pathways.

Basic Information

Product Name	Cyclazosin Hydrochloride
CAS No.	146929-33-1
Molecular Formula	C₂₀H₂₅ClN₄O₂ • HCl
Molecular Weight	425.35 g/mol
Synonyms	Cyclazosin HCl; 5-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-6,7,8,9-tetrahydro-1H-cyclazosin hydrochloride; 1-(2-Methoxyphenyl)-4-[2-(6,7,8,9-tetrahydro-5H-cyclazosin-5-yl)ethyl]piperazine hydrochloride; α-1B Adrenoceptor Antagonist
EINECS	Contact for details

Quality Control

Our Cyclazosin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-purity standards suitable for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.