Description

2'-Deoxyguanosine 5'-Monophosphate, Disodium Salt Hydrate is a high-purity nucleotide derivative essential for biochemical research and pharmaceutical development. This compound serves as a critical building block in molecular biology, enabling studies in DNA synthesis, repair mechanisms, and enzymatic processes. It is primarily utilized by research institutions, diagnostic kit manufacturers, and companies developing antiviral or anticancer therapeutics that target nucleotide metabolism.

Application

• Biochemical Research: Used as a substrate or standard in enzymatic assays, polymerase studies, and investigations into DNA replication and repair pathways.
• Pharmaceutical Intermediates: Serves as a key starting material or precursor in the synthesis of nucleoside analog prodrugs and antiviral agents.
• Molecular Diagnostics: Employed in the formulation of PCR mixes, sequencing reactions, and as a component in non-radioactive labeling kits.
• Cell Culture & Media Supplements: Can be used as a defined nutrient component in specialized cell culture media for sensitive biological production.
• Enzyme Cofactor Studies: Acts as a cofactor or allosteric modulator in studies of guanylate cyclase and related signaling enzymes.
• Reference Standard: Provides a high-purity analytical standard for quality control in pharmaceutical manufacturing and academic research.

Basic Information

Product Name	2'-Deoxyguanosine 5'-Monophosphate, Disodium Salt Hydrate
CAS No.	146877-98-7
Molecular Formula	C10H12N5Na2O7P · xH2O
Molecular Weight	391.18 (anhydrous basis)
Synonyms	dGMP Disodium Salt; 2'-Deoxyguanosine-5'-monophosphoric acid disodium salt; Deoxyguanylic acid disodium salt; 5'-dGMP Na2; Sodium 2'-deoxyguanylate; Guanosine-5'-monophosphate, 2'-deoxy-, disodium salt; dG-5'-P Disodium Salt; Disodium 2'-deoxy-5'-guanylate
EINECS	Contact for details

Quality Control

Our 2'-Deoxyguanosine 5'-Monophosphate, Disodium Salt Hydrate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 10.0%
pH (1% Solution)	6.5 - 8.5
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Clear, colorless solution in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.