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Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X) CAS NO 146877-92-1


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CAS No.:146877-92-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X) is a high-purity sodium salt derivative of a key nucleotide analog, essential for advanced biochemical and pharmaceutical research. This compound matters because it offers a stable, water-soluble form critical for precise formulation in sensitive applications, ensuring reliable and reproducible experimental results. It is primarily needed by pharmaceutical R&D laboratories and biochemical manufacturers developing nucleoside-based therapeutics, diagnostic assays, and enzymatic studies.

Application

  • Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside prodrugs.
  • Biochemical Research: Used as a substrate or reference standard in enzymatic studies involving kinases, polymerases, and other nucleotide-processing enzymes.
  • Diagnostic Reagent Manufacturing: Incorporated into the production of high-sensitivity assay kits for molecular diagnostics and cellular metabolism studies.
  • Cell Culture & Media Supplement: Acts as a specialized component in advanced cell culture media for metabolic pathway research.
  • Reference Standard: Employed as a high-purity calibrant in analytical methods like HPLC and LC-MS for quality control in pharmaceutical production.
  • Precursor for Labeled Compounds: Used in the synthesis of isotopically labeled (e.g., 13C, 15N) nucleotides for metabolic tracing and NMR studies.

Basic Information

Product Name Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X)
CAS No. 146877-92-1
Molecular Formula C10H12N5Na2O7P • xH2O
Molecular Weight Contact for details
Synonyms Sodium Adenosine 5'-Monophosphate Hydrate; 5'-AMP Sodium Salt Hydrate; Adenosine 5'-Monophosphate Disodium Salt; AMP-Na2; Adenosine-5'-monophosphoric acid disodium salt; 5'-Adenylic acid disodium salt; Disodium 5'-adenylate; Disodium adenosine 5'-phosphate
EINECS Contact for details

Quality Control

Our Sodium Adenosine 5'-Monophosphate Hydrate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and in-vitro diagnostic use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request, supporting compliance with internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation and ensure long-term stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 98.0% (anhydrous basis)
Water Content (KF) Contact for details
pH (5% Solution) 6.5 - 8.5
Heavy Metals < 10 ppm
Residual Solvents (GC) Complies with ICH guidelines
Bacterial Endotoxins < 0.5 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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