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Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X) CAS NO 146877-92-1
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CAS No.:146877-92-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X) is a high-purity sodium salt derivative of a key nucleotide analog, essential for advanced biochemical and pharmaceutical research. This compound matters because it offers a stable, water-soluble form critical for precise formulation in sensitive applications, ensuring reliable and reproducible experimental results. It is primarily needed by pharmaceutical R&D laboratories and biochemical manufacturers developing nucleoside-based therapeutics, diagnostic assays, and enzymatic studies.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside prodrugs.
- Biochemical Research: Used as a substrate or reference standard in enzymatic studies involving kinases, polymerases, and other nucleotide-processing enzymes.
- Diagnostic Reagent Manufacturing: Incorporated into the production of high-sensitivity assay kits for molecular diagnostics and cellular metabolism studies.
- Cell Culture & Media Supplement: Acts as a specialized component in advanced cell culture media for metabolic pathway research.
- Reference Standard: Employed as a high-purity calibrant in analytical methods like HPLC and LC-MS for quality control in pharmaceutical production.
- Precursor for Labeled Compounds: Used in the synthesis of isotopically labeled (e.g., 13C, 15N) nucleotides for metabolic tracing and NMR studies.
Basic Information
| Product Name | Sodium ((2R,3S,4R,5R)-5-(6-Amino-9H-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl)Methyl Phosphate Hydrate(2:1:X) |
| CAS No. | 146877-92-1 |
| Molecular Formula | C10H12N5Na2O7P • xH2O |
| Molecular Weight | Contact for details |
| Synonyms | Sodium Adenosine 5'-Monophosphate Hydrate; 5'-AMP Sodium Salt Hydrate; Adenosine 5'-Monophosphate Disodium Salt; AMP-Na2; Adenosine-5'-monophosphoric acid disodium salt; 5'-Adenylic acid disodium salt; Disodium 5'-adenylate; Disodium adenosine 5'-phosphate |
| EINECS | Contact for details |
Quality Control
Our Sodium Adenosine 5'-Monophosphate Hydrate is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and in-vitro diagnostic use. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request, supporting compliance with internal quality protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation and ensure long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Assay (HPLC) | ≥ 98.0% (anhydrous basis) |
| Water Content (KF) | Contact for details |
| pH (5% Solution) | 6.5 - 8.5 |
| Heavy Metals | < 10 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Bacterial Endotoxins | < 0.5 EU/mg (if applicable) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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