Description

Thiomarinol is a unique sulfur-containing marine natural product with significant biological activity. This compound matters as a potent antibiotic agent, exhibiting strong inhibitory effects against a range of Gram-positive bacteria, including methicillin-resistant *Staphylococcus aureus* (MRSA). It is primarily needed by researchers in pharmaceutical development and microbiology for the study of novel antibiotic mechanisms and as a lead compound for new therapeutic agents. The product is supplied as Thiomarinol CAS NO 146697-04-3 to ensure precise identification for research and development purposes.

Application

• Pharmaceutical Research: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of new antibiotic classes.
• Microbiological Studies: Used as a potent tool compound to investigate bacterial resistance mechanisms and novel modes of antibacterial action.
• Lead Compound Optimization: Acts as a structural scaffold for medicinal chemistry programs aimed at creating derivatives with improved pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for fundamental studies on marine natural products and their biosynthesis.
• Biochemical Assays: Utilized in high-throughput screening and in vitro assays to evaluate antimicrobial potency.

Basic Information

Product Name	Thiomarinol
CAS No.	146697-04-3
Molecular Formula	C₂₃H₃₀N₂O₇S₂
Molecular Weight	510.62 g/mol
Synonyms	Thiomarinol; Thiomarinol A; Antibiotic AL-1; Thiomarinol antibiotic; (2E,4E,6E,8E)-9-[(2R,3S,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(1E,3E,5E,7E)-8-[(2S,3S)-3-hydroxy-2-[(1E,3E,5E)-6-(2-methyl-1,3-thiazol-4-yl)hexa-1,3,5-trien-1-yl]pyrrolidin-1-yl]-8-oxoocta-1,3,5,7-tetraen-1-yl]amino]oxan-2-yl]oxy]nona-2,4,6,8-tetraenoic acid
EINECS	Contact for details

Quality Control

Our Thiomarinol is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification by spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. The container should be kept in a dry, well-ventilated area designated for research chemicals.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.