Description

Cyclohexanecarbonyl Chloride, 4-Butyl-, cis- (9Ci) is a specialized organic intermediate featuring a cis-configured butyl-substituted cyclohexane ring and a reactive acid chloride functional group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its stereochemistry and reactivity are leveraged to create active ingredients. It is primarily needed by R&D chemists and process development scientists working on advanced organic synthesis, including the production of fine chemicals and novel materials. The CAS number for this compound is 146606-05-5.

Application

This versatile intermediate is employed in several high-value synthetic pathways:

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a specific cis-cyclohexane conformation.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the butyl-cyclohexyl moiety imparts desired biological activity.
• Liquid Crystal & Advanced Material Production: Acts as a building block for creating stereochemically defined components in liquid crystal displays (LCDs) and other specialty polymers.
• Organic Synthesis & Research: A valuable reagent in academic and industrial laboratories for constructing complex carbon skeletons and introducing the carbonyl chloride group for further derivatization.
• Flavor & Fragrance Industry: Potential use in the synthesis of musky or woody aroma chemicals, leveraging the stability of the cyclohexane ring.

Basic Information

Product Name	Cyclohexanecarbonyl Chloride, 4-Butyl-, cis- (9Ci)
CAS No.	146606-05-5
Molecular Formula	C11H19ClO
Molecular Weight	202.72 g/mol
Synonyms	cis-4-Butylcyclohexanecarbonyl chloride; (cis)-4-Butylcyclohexanecarboxylic acid chloride; 4-Butylcyclohexanecarbonyl chloride, cis-; 4-n-Butylcyclohexanecarboxylic acid chloride, cis-; cis-4-n-Butylcyclohexanecarbonyl Chloride; (4-cis-Butylcyclohexyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarbonyl Chloride, 4-Butyl-, cis- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, isomeric purity (cis- content), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and classification as a strong acid/organic solvent, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, heat, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (Assay by GC/HPLC)	≥ 97.0%
Isomeric Purity (cis- isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.