Description

Pradimicin S CAS NO 146446-02-8 is a benzo[a]naphthacenequinone antibiotic belonging to the pradimicin family, a class of compounds known for their unique carbohydrate-binding properties. This compound is valued for its potent antifungal activity, particularly against pathogenic Candida species, by selectively binding to cell wall mannan. It serves as a critical reference standard and research-grade biochemical for pharmaceutical R&D, microbiology, and antifungal mechanism of action studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of pradimicin-class antibiotics in research and quality control laboratories.
• Antifungal Mechanism Research: Employed in biochemical studies to investigate the unique mannose-binding mode of action and its effects on fungal cell walls.
• Microbiological Assays: Serves as a positive control in antifungal susceptibility testing and screening assays against yeast and fungal pathogens.
• Lead Compound Development: Provides a structural template for the semi-synthesis and modification of novel antifungal agents with improved properties.
• Academic & Institutional Research: Utilized in university and institutional labs for studies in medicinal chemistry, microbiology, and infectious disease.

Basic Information

Product Name	Pradimicin S
CAS No.	146446-02-8
Molecular Formula	C₄₂H₄₅NO₁₇
Molecular Weight	859.81 g/mol
Synonyms	Pradimicin S; BMY-28864; Antibiotic BMY 28864; (1S,12S,14S,15R,16S,18R,19R,24S,26R,28S,29R,31S,33R,35S,36R,38S,39R,41S)-15,16,18,19,24,26,28,29,31,33,35,36,38,39,41-Pentadecahydroxy-12-methoxy-3,10-dimethyl-14,29-bis(1-methylethyl)-1,4,11,13,22,25,30,34,37,40,42-undecaoxo-1H,13H-2,7:23,27-dimethenobenzo[a]naphthaceno[9,8-fg]pentacene-5-carboxamide; Pradimicin S (BMY-28864)
EINECS	Contact for details

Quality Control

Our Pradimicin S is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Identity and purity are confirmed through a combination of advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to Orange Powder
Identification (HPLC)	Conforms to Reference Standard
Identification (IR)	Conforms to Structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.