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4-Isothiocyanatophenyl α-D-Galactopyranoside CAS NO 146194-63-0
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CAS No.:146194-63-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Isothiocyanatophenyl α-D-Galactopyranoside is a specialized glycoside derivative designed for advanced biochemical conjugation and labeling applications. This compound is valued for its ability to serve as a critical linker, enabling the specific attachment of galactose moieties to target molecules or surfaces via its reactive isothiocyanate group. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, diagnostic assay development, and pharmaceutical research for creating probes, sensors, and targeted delivery systems.
Application
- Glycoconjugate Synthesis: Key intermediate for the chemical synthesis of neoglycoconjugates and glycoclusters for biological studies.
- Diagnostic Reagent Manufacturing: Used in the development of enzyme-linked immunosorbent assays (ELISA) and other immunoassays for detecting specific carbohydrate-binding proteins (lectins).
- Biomolecule Labeling: Conjugation agent for labeling proteins, antibodies, or peptides with galactose epitopes to study carbohydrate-protein interactions.
- Cell Surface Engineering: Tool for modifying cell surfaces with galactose residues to investigate cell adhesion, signaling, and targeted drug delivery mechanisms.
- Affinity Chromatography Ligand: Immobilized onto solid supports to create resins for the purification of galactose-binding lectins and receptors.
- Pharmaceutical Research: Building block in the research and development of novel glycotherapeutic agents and drug delivery vehicles.
Basic Information
| Product Name | 4-Isothiocyanatophenyl α-D-Galactopyranoside |
| CAS No. | 146194-63-0 |
| Molecular Formula | C₁₃H₁₅NO₇S |
| Molecular Weight | 329.33 g/mol |
| Synonyms | p-Isothiocyanatophenyl α-D-galactopyranoside; 4-Isothiocyanatophenyl α-D-galactoside; Phenyl 4-isothiocyanato-α-D-galactopyranoside; α-D-Galactopyranoside, 4-isothiocyanatophenyl; Galactose-PITC; 4-ITC-Phenyl-α-Gal; p-Isothiocyanatophenyl-α-D-galactoside |
| EINECS | Contact for details |
Quality Control
Our 4-Isothiocyanatophenyl α-D-Galactopyranoside is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 2.0% |
| Solubility | Soluble in DMSO, DMF; slightly soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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