Description

5-Epi Emtricitabine is a key nucleoside analog and a stereoisomer of the widely used antiviral drug Emtricitabine. This compound is of significant value in pharmaceutical research and development, particularly for studying structure-activity relationships and metabolic pathways. It serves as a critical intermediate and reference standard for scientists in the pharmaceutical and biotechnology sectors focused on antiviral therapies, including those targeting HIV and hepatitis B.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel nucleoside-based antiviral agents.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Metabolic Studies: Employed in research to investigate the metabolic pathways and stereoselective processing of emtricitabine and related compounds.
• Structure-Activity Relationship (SAR) Research: A vital tool for medicinal chemists to understand how structural modifications impact the biological activity of nucleoside analogs.
• Process Development: Used in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Academic & Institutional Research: Supports fundamental virology and medicinal chemistry research in universities and government institutions.

Basic Information

Product Name	5-Epi Emtricitabine
CAS No.	145986-26-1
Molecular Formula	C8H10FN3O3S
Molecular Weight	247.25 g/mol
Synonyms	5'-Deoxy-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; 5-Fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; FTC Epimer; Emtricitabine Epimer; (-)-FTC; 5-Epi-FTC; 2',3'-Dideoxy-5-fluoro-3'-thiacytidine Epimer
EINECS	Contact for details

Quality Control

Our 5-Epi Emtricitabine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.