Description

7-Ketocholesteryl-3-Oleate is a high-purity, synthetic cholesterol derivative where the 7-position is oxidized to a ketone and the 3-position is esterified with oleic acid. This specific molecular architecture makes it a valuable intermediate and reference standard in advanced lipid research and pharmaceutical development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for studying oxidative stress, lipid metabolism, and as a precursor for synthesizing more complex bioactive molecules.

Application

• Biochemical Research: Serves as a critical reference standard and intermediate in the study of cholesterol oxidation products (oxysterols) and their biological roles.
• Pharmaceutical Development: Used as a key starting material or synthetic precursor in the research and development of novel therapeutic agents targeting lipid-related pathways.
• Analytical Chemistry: Employed as a high-purity calibration standard in chromatographic (HPLC, GC) and mass spectrometric analyses for accurate quantification of sterol derivatives.
• Nutraceutical & Cosmetic Research: Investigated for its potential effects in models of skin aging and cellular metabolism within advanced R&D formulations.

Basic Information

Product Name	7-Ketocholesteryl-3-Oleate
CAS No.	145889-56-1
Molecular Formula	C55H88O3
Molecular Weight	797.3 g/mol
Synonyms	7-Oxocholesteryl Oleate; Cholest-5-en-3β-ol, 7-oxo-, 3-oleate; 7-Ketocholesterol Oleate; 7-KC Oleate; 7-Oxo-cholesteryl-3-oleate; Oleic acid 7-ketocholesteryl ester; (3β)-7-Oxocholest-5-en-3-yl (9Z)-9-octadecenoate
EINECS	Contact for details

Quality Control

Every batch of 7-Ketocholesteryl-3-Oleate is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the sealed container under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation. Allow the product to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.