Description

2-(Propylthio)Adenosine-5'-o-(β,γ-Difluoromethylene)Triphosphatetetrasodiumsalt is a chemically modified nucleotide analog, specifically a stabilized ATP derivative, designed for advanced biochemical research and therapeutic development. Its core value lies in its resistance to enzymatic hydrolysis, making it a crucial tool for studying ATP-dependent processes and as a potential prodrug or enzyme inhibitor. This high-purity compound is essential for researchers and developers in pharmaceutical discovery, enzymology, and molecular biology, particularly for investigating purinergic signaling pathways and kinase activity.

Application

• Biochemical Research: As a non-hydrolyzable ATP analog for studying enzyme kinetics, particularly ATPases, kinases, and other ATP-binding proteins.
• Pharmaceutical Development: Investigation as a potential prodrug or active pharmaceutical ingredient (API) in therapeutic areas targeting purinergic receptors.
• Enzymology Studies: Used to probe the mechanism of action of enzymes that utilize ATP as a substrate or cofactor.
• Signal Transduction Research: Tool compound for modulating P2 receptor signaling pathways in cellular and in vitro assays.
• Diagnostic Reagent Development: Potential component in diagnostic kits for measuring ATP-related enzymatic activity.
• Stable Isotope Labeling: Serves as a precursor for synthesizing isotopically labeled probes for metabolic tracing studies.

Basic Information

Product Name	2-(Propylthio)Adenosine-5'-o-(β,γ-Difluoromethylene)Triphosphatetetrasodiumsalt
CAS No.	145783-24-0
Molecular Formula	C₁₈H₂₃F₂N₅O₁₂P₃S · 4Na
Molecular Weight	Contact for details
Synonyms	Adenosine-5'-[β,γ-difluoromethylene] triphosphate, 2-(propylthio)-, tetrasodium salt
2-(Propylthio)-ATP-β,γ-difluoromethylene tetrasodium
2-(n-Propylthio)-adenosine-5'-(β,γ-difluoromethylene)triphosphate tetrasodium salt
2-S-Propyl-ATP-β,γ-CHF₂ tetrasodium salt
Non-hydrolyzable 2-thioalkyl ATP analog
P1-(Adenosine-5')-P3-[difluoromethylene] triphosphate, 2-(propylthio)- derivative
Stabilized ATP analog, 2-propylthio substituted
EINECS	Contact for details

Quality Control

Our production of this high-value biochemical adheres to stringent quality protocols. Each batch is characterized and purified to meet exacting standards for pharmaceutical and research-grade applications. Comprehensive analysis includes HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
pH (1% Solution)	6.0 - 8.0
Heavy Metals	≤ 20 ppm
Biological Activity	Assay-dependent; COA provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.