Description

(4-2-Aminopurin-9-Yl)-1,3-Dioxolane-2-Methanol is a high-purity nucleoside analogue derivative, a key intermediate in advanced pharmaceutical synthesis. This compound is critical for research and development in antiviral and anticancer therapeutic agents, offering a versatile building block for novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on nucleoside chemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogues.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting viral polymerases.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to nucleic acid metabolism.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals for life sciences.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	(4-2-Aminopurin-9-Yl)-1,3-Dioxolane-2-Methanol
CAS No.	145514-01-8
Molecular Formula	C9H11N5O3
Molecular Weight	237.22 g/mol
Synonyms	2-Amino-9-[(1,3-dioxolan-2-yl)methyl]-9H-purine; 2-Amino-9-[(1,3-dioxolan-2-yl)methyl]purine; 9-[(1,3-Dioxolan-2-yl)methyl]guanine; 2-Aminopurine dioxolane derivative; 2-AP-Dioxolane; Guanosine analogue intermediate; 1,3-Dioxolane-2-methanol, 4-(2-aminopurin-9-yl)-
EINECS	Contact for details

Quality Control

Our (4-2-Aminopurin-9-Yl)-1,3-Dioxolane-2-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.