Description

4H-Cyclopenta-1,3-Dioxol-4-One, 6-[[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Methyl]Tetrahydro-2,2-Dimethyl-, (3Ar,6R,6Ar)- is a sophisticated chiral building block featuring a protected hydroxyl group, making it a critical intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures with high stereochemical fidelity, essential for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in the areas of antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of nucleoside analogues and other antiviral compounds targeting specific viral enzymes.
• Anticancer Agent Synthesis: Serves as a building block for creating novel chemotherapeutic agents with targeted mechanisms of action.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce specific chiral centers into complex organic molecules.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	4H-Cyclopenta-1,3-Dioxol-4-One, 6-[[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Methyl]Tetrahydro-2,2-Dimethyl-, (3Ar,6R,6Ar)-
CAS No.	145307-55-7
Molecular Formula	C15H28O4Si
Molecular Weight	300.47 g/mol
Synonyms	(3aR,6R,6aR)-6-(((tert-Butyldimethylsilyl)oxy)methyl)tetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-one; 6-((tert-Butyldimethylsilyloxy)methyl)-2,2-dimethyltetrahydro-4H-cyclopenta-1,3-dioxol-4-one; TBDMS-protected cyclopentane derivative; Chiral TBDMS ether of a cyclopentane dioxolone; (3aR,6R,6aR)-6-[[(tert-Butyldimethylsilyl)oxy]methyl]-2,2-dimethyltetrahydro-4H-cyclopenta-1,3-dioxol-4-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) are available upon request, detailing purity, chiral purity (enantiomeric excess), and impurity profiles as determined by advanced analytical techniques including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.