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Deoxycholic Acid Sodium Salt Monohydrate CAS NO 145224-92-6


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CAS No.:145224-92-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Deoxycholic Acid Sodium Salt Monohydrate is a high-purity bile acid derivative widely utilized in pharmaceutical and biochemical research. This compound is valued for its role as a biological detergent and its critical function in fat emulsification and absorption processes. It is an essential raw material and reagent for manufacturers in the pharmaceutical, diagnostic, and life science research sectors, where consistent quality and reliable supply are paramount.

Application

  • Pharmaceutical Intermediates: A key starting material or intermediate in the synthesis of various active pharmaceutical ingredients (APIs) and steroid-based drugs.
  • Biochemical Research: Used as a biological detergent to solubilize membrane proteins and lipids in cell lysis and protein extraction protocols.
  • Diagnostic Reagents: Employed in the formulation of clinical diagnostic kits, particularly those related to liver function and lipid metabolism.
  • Cell Culture & Microbiology: Acts as a selective agent or a component in specialized cell culture media and microbiological assays.
  • Reference Standards: Serves as a certified reference standard (CRS) or pharmacopeial standard for quality control testing in regulated environments.
  • Cosmetic & Dermatological Preparations: Investigated for use in topical formulations, leveraging its properties as a penetration enhancer.

Basic Information

Product Name Deoxycholic Acid Sodium Salt Monohydrate
CAS No. 145224-92-6
Molecular Formula C24H39NaO5 • H2O
Molecular Weight 432.56 g/mol
Synonyms Sodium Deoxycholate Monohydrate; Deoxycholic Acid Sodium Salt Hydrate; Sodium Desoxycholate; 3α,12α-Dihydroxy-5β-cholan-24-oic Acid Sodium Salt Monohydrate; Cholerebic; Desoxycholsäure Natriumsalz Monohydrat; Natrii Deoxycholas; DOCS
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Quality Control

Our Deoxycholic Acid Sodium Salt Monohydrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications suitable for research and pharmaceutical applications. Certificates of Analysis (COA) documenting purity, residual solvents, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Assay (HPLC) ≥ 98.0% (on anhydrous basis)
Water Content (KF) 3.5% - 5.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Specific Rotation +40° to +45° (c=1 in ethanol)
pH (1% Solution) 7.0 - 9.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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