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7-Deaza-A Cep CAS NO 144994-95-6


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CAS No.:144994-95-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Deaza-A Cep is a high-purity nucleoside analog, a critical building block in advanced oligonucleotide synthesis. Its value lies in enabling the development of modified nucleic acid sequences with enhanced stability and specificity for research and therapeutic applications. This compound is essential for pharmaceutical R&D, diagnostic assay development, and academic research focused on antisense technology, siRNA, and aptamers.

Application

  • Pharmaceutical Intermediate: Key raw material for the synthesis of novel antisense oligonucleotides and siRNA therapeutics.
  • Diagnostic Probe Synthesis: Used in manufacturing labeled probes for molecular diagnostics and hybridization assays.
  • Biochemical Research: Fundamental component in studying nucleic acid structure, function, and enzyme interactions.
  • Antiviral Drug Development: Serves as a precursor in the research of nucleoside-based antiviral agents.
  • Synthesis of Modified Oligonucleotides: For creating sequences with improved nuclease resistance and binding affinity.
  • Academic & Contract Research: Supplied to universities and CROs for basic and applied life science research.

Basic Information

Product Name 7-Deaza-A Cep
CAS No. 144994-95-6
Molecular Formula C13H16N4O4
Molecular Weight 292.29 g/mol
Synonyms 7-Deaza-2'-deoxyadenosine-5'-monophosphate morpholidate; 7-Deaza-dAMP Morpholidate; 7-Deaza-2'-deoxyadenylyl-(5'→N)-morpholine-4-carboxamide; 7-Deaza-dA-CE Phosphoramidite precursor; 7-Carba-2'-deoxyadenosine-5'-monophosphomorpholidate; 7-Deaza-dA-CEP; 7-Deaza-2'-deoxyadenosine 5'-(4-morpholine-N,N'-dicyclohexylcarboxamidine)
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Quality Control

Our 7-Deaza-A Cep is manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive oligonucleotide synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards of pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Solubility Soluble in anhydrous acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.