Description

Ethyl 3-Azido-2-Hydroxy-Propionate is a versatile bifunctional organic building block containing both an azide and a hydroxyl group, enabling its use in click chemistry and other synthetic transformations. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), including potential antiviral and anticancer agents.
• Click Chemistry Reagent: The azide group enables efficient Huisgen 1,3-dipolar cycloaddition reactions with alkynes to form triazole linkages, useful in bioconjugation and polymer chemistry.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Modification: Used to introduce azido-functionalized side chains into peptides and proteins for subsequent labeling or cross-linking.
• Polymer & Material Science: Acts as a monomer or cross-linker for creating functional polymers with tailored properties via its reactive handles.
• Chemical Biology Probes: Facilitates the synthesis of activity-based probes and reporter molecules for studying biological processes.
• Ligand & Catalyst Development: Useful for constructing chelating ligands or functionalized catalysts in asymmetric synthesis.

Basic Information

Product Name	Ethyl 3-Azido-2-Hydroxy-Propionate
CAS No.	144787-20-2
Molecular Formula	C5H9N3O3
Molecular Weight	159.14 g/mol
Synonyms	Ethyl 3-Azido-2-hydroxypropanoate; 2-Hydroxy-3-azidopropionic Acid Ethyl Ester; 3-Azido-2-hydroxypropionic Acid Ethyl Ester; Ethyl 2-Hydroxy-3-azidopropionate; Azidohydroxypropionate Ethyl Ester; Glycidyl Azide Ester Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Ethyl 3-Azido-2-Hydroxy-Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for production relevant to pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to the presence of the azide functional group, appropriate safety protocols for handling azide compounds should be followed.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.