Description

Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, trans- (9Ci) is a high-purity, chiral organic building block of significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the specific stereochemistry of the cyclopentane ring is critical for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of novel polymers and liquid crystals with specific optical properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring a defined trans-stereochemistry on a functionalized cyclopentane scaffold.
• Academic and Industrial R&D: Used in methodological development and exploration of new synthetic pathways in organic chemistry.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, trans- (9Ci)
CAS No.	144728-23-4
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	trans-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid Ethyl Ester; Ethyl trans-2-(Chlorocarbonyl)cyclopentanecarboxylate; trans-1-Carbethoxy-2-chlorocarbonylcyclopentane; (1R,2S)-rel-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid Ethyl Ester; (1S,2R)-rel-2-(Chlorocarbonyl)cyclopentanecarboxylic Acid Ethyl Ester; Cyclopentanecarboxylic acid, 2-(chlorocarbonyl)-, ethyl ester, trans-; Ethyl (1R,2S)-2-(chlorocarbonyl)cyclopentanecarboxylate (racemic)
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-(Chlorocarbonyl)-, Ethyl Ester, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain purity and prevent hydrolysis. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.