Description

Olmesartan is a potent and selective angiotensin II receptor blocker (ARB) used as an active pharmaceutical ingredient (API). This high-purity compound is critical for the formulation of antihypertensive medications, offering effective blood pressure control. It is essential for pharmaceutical manufacturers and research institutions developing cardiovascular therapies and generic drug products.

Application

• Primary Pharmaceutical Ingredient: Core API in the manufacture of Olmesartan medoxomil tablets and other dosage forms for treating hypertension.
• Generic Drug Production: Sourcing for companies developing bioequivalent versions of branded antihypertensive medications.
• Combination Therapies: Used in fixed-dose combination drugs, often paired with other antihypertensives like amlodipine or hydrochlorothiazide.
• Pharmaceutical Research & Development: Key intermediate or reference standard in preclinical and clinical studies for new cardiovascular drugs.
• Contract Manufacturing: Supply for CDMOs (Contract Development and Manufacturing Organizations) producing finished dosage forms.
• Analytical Testing: Serves as a certified reference material (CRM) for quality control and assay validation in analytical laboratories.

Basic Information

Product Name	Olmesartan
CAS No.	144689-24-7
Molecular Formula	C29H30N6O6
Molecular Weight	558.59 g/mol
Synonyms	Olmesartan acid; RN-132798Y; Benzoic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid; CS-866 (free acid); (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]imidazole-5-carboxylate (medoxomil ester); Olmesartan Medoxomil impurity C
EINECS	Contact for details

Quality Control

Our Olmesartan is manufactured under strict quality management systems. Each batch is tested to ensure compliance with major pharmacopoeial standards such as USP and EP. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles to support your regulatory filings and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.