Description

Pixantrone Dimaleate is a synthetic anthracenedione derivative and a key pharmaceutical intermediate. This compound is valued for its role in the development of chemotherapeutic agents, offering a structural basis for drugs with antineoplastic activity. It is primarily required by pharmaceutical R&D laboratories and manufacturers engaged in the synthesis of novel oncology therapeutics. Global suppliers seek this high-purity intermediate for its critical function in advanced drug development pipelines.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of the active pharmaceutical ingredient (API) Pixantrone, a chemotherapeutic agent.
• Oncology Drug Development: Serves as a crucial building block in R&D for novel antineoplastic and antitumor compounds.
• Biochemical Research: Used in laboratory studies to investigate the mechanisms of topoisomerase II inhibition and DNA intercalation.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and quality assurance (QA) for pharmaceutical manufacturing.
• Preclinical Studies: Utilized in the preparation of formulations for pharmacokinetic and toxicological evaluation in animal models.

Basic Information

Product Name	Pixantrone Dimaleate
CAS No.	144675-97-8
Molecular Formula	C29H32N6O10
Molecular Weight	624.60 g/mol
Synonyms	Pixantrone Dimaleate Salt; BBR 2778 Dimaleate; 6,9-Bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione Dimaleate; Benzo[g]isoquinoline-5,10-dione, 6,9-bis[(2-aminoethyl)amino]-, (2Z)-2-butenedioate (1:2); Pixantrone Maleate; NSC 366140 (Dimaleate); DB 144675-97-8
EINECS	Contact for details

Quality Control

Our Pixantrone Dimaleate is manufactured under strict quality systems to ensure it meets the exacting standards required for pharmaceutical development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality commitment ensures reliable supply and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C (59-77°F). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.