Description

8-Aht-Cgmp (All Sodium Salt) is a specialized biochemical compound, a sodium salt derivative of 8-AHT-cGMP, which serves as a key research tool in cellular signaling studies. This product is essential for researchers investigating cyclic nucleotide-gated ion channels and phosphodiesterase activity, providing a stable and soluble form for experimental use. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on cardiovascular, neurological, and metabolic disease pathways.

Application

• Biochemical Research: As a cell-permeable analog of cGMP for studying intracellular signal transduction mechanisms.
• Pharmaceutical Development: A reference standard and tool compound in drug discovery programs targeting guanylyl cyclase and related pathways.
• Enzyme Studies: Used as a substrate or inhibitor in assays for phosphodiesterase (PDE) enzyme activity and selectivity.
• Ion Channel Research: For the activation and characterization of cyclic nucleotide-gated (CNG) ion channels in sensory biology.
• Cell Biology: Investigation of cellular processes such as smooth muscle relaxation, platelet aggregation, and neuronal plasticity.
• Diagnostic Reagent Manufacturing: A potential component in the development of high-sensitivity diagnostic kits for research use.

Basic Information

Product Name	8-Aht-Cgmp (All Sodium Salt)
CAS No.	144510-13-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	8-(4-Aminophenylthio)guanosine-3',5'-cyclic monophosphate sodium salt; 8-(p-Aminophenylthio)-cGMP sodium salt; 8-APTC-cGMP sodium salt; 8-AHT-cGMP, sodium salt; cGMP derivative, sodium salt; 8-(4-Aminophenylthio)-cyclic GMP sodium salt; All Sodium Salt of 8-AHT-cGMP
EINECS	Contact for details

Quality Control

Our 8-Aht-Cgmp (All Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (UV)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.