Description

2-Pyridineacetyl Chloride, α-Oxo- (9Ci) is a highly reactive and versatile acid chloride derivative used as a key building block in organic synthesis. Its value lies in its ability to introduce the 2-pyridylglyoxyloyl moiety, a functional group of significant interest in medicinal chemistry and materials science. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine ring contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating novel chelating ligands and organometallic catalysts.
• Peptide Mimetics and Bioconjugation: Facilitates the incorporation of heterocyclic structures into peptide backbones or for labeling biomolecules.
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials with specific optoelectronic properties.
• Chemical Biology Probes: Used to develop activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Product Name	2-Pyridineacetyl Chloride, α-Oxo- (9Ci)
CAS No.	143668-51-3
Molecular Formula	C7H4ClNO2
Molecular Weight	169.56 g/mol
Synonyms	2-Oxo-2-(pyridin-2-yl)acetyl chloride; 2-Pyridylglyoxyloyl chloride; 2-Pyridyl-oxoacetyl chloride; α-Oxo-2-pyridineacetyl chloride; Pyruvoyl chloride, 2-pyridyl-; (2-Pyridinyl)oxoacetyl chloride; 2-Pyridinecarbonyl chloride, formyl-
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridineacetyl Chloride, α-Oxo- (9Ci) is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as NMR, HPLC, and GC is supplied with each shipment to guarantee reproducible performance and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.