Description

9,11-Seco-3,6,11-Trihydroxy-24-Methylenecholest-7-En-9-One is a specialized secosteroid derivative, a key intermediate in the synthesis of complex bioactive molecules. Its unique structural framework, featuring a seco-B ring and multiple hydroxyl groups, makes it a valuable building block for pharmaceutical research and development. This compound is primarily utilized by research institutions and fine chemical manufacturers focused on steroid chemistry, vitamin D analogs, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of advanced vitamin D analogs and other secosteroid-based active pharmaceutical ingredients (APIs).
• Steroid Research: Serves as a key scaffold in academic and industrial research for studying steroid receptor interactions and metabolic pathways.
• Fine Chemical Synthesis: Used as a sophisticated building block for constructing complex natural product derivatives and novel chemical entities.
• Biochemical Tool Compound: Employed in biochemical assays to investigate cellular signaling mechanisms related to steroid hormones.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	9,11-Seco-3,6,11-Trihydroxy-24-Methylenecholest-7-En-9-One
CAS No.	143625-40-5
Molecular Formula	C₂₈H₄₄O₄
Molecular Weight	444.65 g/mol
Synonyms	24-Methylene-9,11-secocholesta-5,7-diene-3,6,11-triol-9-one; 9,11-Seco-3,6,11-trihydroxy-24-methylen-7-en-9-on-cholestan; (24E)-24-Methylene-9,11-secocholesta-5,7-diene-3,6,11-triol-9-one; Secosteroid intermediate; Vitamin D analog intermediate
EINECS	Contact for details

Quality Control

Our 9,11-Seco-3,6,11-Trihydroxy-24-Methylenecholest-7-En-9-One is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.