Description

Cyclobutanecarbonyl Chloride, 3-Ethyl-, trans- (9Ci) is a specialized organic building block featuring a functionalized cyclobutane ring system. This compound matters as a high-value intermediate for constructing complex molecular architectures in advanced synthetic chemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring a constrained, trans-substituted cyclobutane scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with unique steric and electronic properties.
• Material Science Research: Serves as a monomer or cross-linking agent precursor in the development of advanced polymers with specific ring-strain characteristics.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands or organocatalysts where the cyclobutane structure imparts specific stereochemical control.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex fragrance molecules, flavors, or other specialty chemicals.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3-Ethyl-, trans- (9Ci)
CAS No.	143610-61-1
Molecular Formula	C7H11ClO
Molecular Weight	146.61 g/mol
Synonyms	trans-3-Ethylcyclobutanecarbonyl chloride; (1r,3r)-3-Ethylcyclobutanecarboxylic acid chloride; 3-Ethylcyclobutanecarbonyl chloride, trans-; Cyclobutanecarbonyl chloride, 3-ethyl-, (1R,3R)-rel-; (rel)-(1R,3R)-3-Ethylcyclobutanecarboxylic acid chloride; 143610-61-1; trans-3-Ethylcyclobutanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3-Ethyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Isomeric Purity (trans-)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.