Description

Cyclobutanecarbonyl Chloride, 3-Butyl-, trans- (9Ci) is a specialized organic acid chloride derivative of cyclobutane, serving as a critical chiral building block in advanced organic synthesis. This compound matters for its ability to introduce the sterically defined trans-3-butylcyclobutanecarbonyl moiety into target molecules, enabling precise control over molecular architecture. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting specific receptor binding.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the specific spatial orientation of the butyl group can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of monomers or functional polymers with tailored thermal or mechanical properties derived from the cyclobutane ring structure.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, exploring new cyclobutane-based transformations and ring-opening reactions.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3-Butyl-, trans- (9Ci)
CAS No.	143610-57-5
Molecular Formula	C9H15ClO
Molecular Weight	174.67 g/mol
Synonyms	trans-3-Butylcyclobutanecarbonyl Chloride; (1r,3r)-3-Butylcyclobutanecarbonyl Chloride; (trans)-3-Butylcyclobutanecarboxylic Acid Chloride; 3-Butylcyclobutanecarbonyl Chloride, trans-; Cyclobutanecarboxylic Acid, 3-Butyl-, Chloride, trans-; (1R,3R)-3-Butyl-1-cyclobutanecarbonyl Chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3-Butyl-, trans- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.