Description

Benzoyl Chloride, 3-Ethynyl- (9Ci) CAS NO 143587-37-5 is a specialized organic building block featuring both a reactive benzoyl chloride group and an ethynyl (acetylene) moiety. This unique bifunctional structure makes it a valuable intermediate for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting kinase inhibition or requiring acetylene-linked pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, resins, and advanced organic frameworks.
• Chemical Research: A versatile reagent for Sonogashira coupling and other palladium-catalyzed reactions to create conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal-organic catalysis and coordination chemistry.
• Dye and Pigment Intermediate: Used in the development of advanced organic dyes and functional colorants.

Basic Information

Product Name	Benzoyl Chloride, 3-Ethynyl- (9Ci)
CAS No.	143587-37-5
Molecular Formula	C9H5ClO
Molecular Weight	164.59 g/mol
Synonyms	3-Ethynylbenzoyl chloride; m-Ethynylbenzoyl chloride; 3-Ethynylbenzoic acid chloride; 1-(3-Chlorocarbonylphenyl)ethyne; Benzoyl chloride, m-ethynyl-; 3-Acetylene benzoyl chloride; 3-(Chlorocarbonyl)phenylacetylene
EINECS	Contact for details

Quality Control

Our Benzoyl Chloride, 3-Ethynyl- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C or as specified on the label. Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.