Description

1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclopentyl-3-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its highly reactive carbonyl chloride group, which enables efficient amide bond formation and serves as a key intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation pesticides, herbicides, and fungicides, leveraging the pyrazole core's bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal or mechanical properties.
• Chemical Biology Probes: Employed to create labeled compounds or activity-based probes for studying enzyme function and biological pathways.
• Ligand Synthesis for Catalysis: Used to construct complex chelating ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclopentyl-3-Methyl- (9Ci)
CAS No.	143469-40-3
Molecular Formula	C10H13ClN2O
Molecular Weight	212.68 g/mol
Synonyms	1-Cyclopentyl-3-methyl-1H-pyrazole-5-carbonyl chloride; 1-Cyclopentyl-3-methyl-1H-pyrazole-5-carboxylic acid chloride; 1-Cyclopentyl-3-methylpyrazole-5-carbonyl chloride; 3-Methyl-1-cyclopentyl-1H-pyrazole-5-carbonyl chloride; 1-Cyclopentyl-3-methyl-1H-pyrazole-5-carboxyl chloride; Cyclopentyl-methyl-pyrazole-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclopentyl-3-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.