Description

Fosfomycin Calcium Salt CAS NO 143292-57-3 is the calcium salt form of the broad-spectrum antibiotic fosfomycin, offering enhanced stability and handling properties. This compound is valued for its unique bactericidal mechanism, inhibiting bacterial cell wall synthesis at an early stage, which makes it effective against a range of Gram-positive and Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) and intermediate primarily required by pharmaceutical manufacturers for the production of oral antibiotic formulations, veterinary medicines, and in clinical research for combating resistant infections.

Application

• Pharmaceutical API: Primary use as the active ingredient in oral antibiotic medications for human use.
• Veterinary Pharmaceuticals: Formulation of antibacterial treatments for livestock and companion animals.
• Clinical Research: Used in studies focusing on antibiotic resistance and novel therapeutic combinations.
• Intermediate Synthesis: Serves as a key precursor for the synthesis of other fosfomycin derivatives and salts.
• Reference Standard: Employed as a high-purity standard in quality control laboratories for HPLC and microbiological assays.

Basic Information

Product Name	Fosfomycin Calcium Salt
CAS No.	143292-57-3
Molecular Formula	C3H5CaO4P
Molecular Weight	176.12 g/mol
Synonyms	Fosfomycin Calcium; Calcium Fosfomycin; (1R,2S)-1,2-Epoxypropylphosphonic Acid Calcium Salt; (-)-(1R,2S)-1,2-Epoxypropylphosphonic Acid Calcium Salt; Fosfomycin Ca; Phosphomycin Calcium Salt; MK-0955 Calcium Salt; FOM-Ca
EINECS	Contact for details

Quality Control

Our Fosfomycin Calcium Salt is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with typical specifications aligning with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results for identity, assay, purity, and related substances. We support compliance with cGMP, ISO standards, and relevant regulatory frameworks like REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	-12.0° to -14.0° (c=1 in H2O)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13 criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.