Description

2,4-Bis(Trifluoromethyl)Benzyl Alcohol is a high-value fluorinated organic intermediate characterized by its benzyl alcohol core flanked by two powerful electron-withdrawing trifluoromethyl groups. This unique structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and electronic properties are required. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing next-generation compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF3 groups improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing thermal stability and optical properties.
• Polymer & Resin Modifier: Incorporated to create specialty polymers with improved chemical resistance, lower dielectric constants, and enhanced surface properties.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalysis in asymmetric synthesis.
• Organic Synthesis Building Block: A versatile reagent for introducing the bis(trifluoromethyl)benzyl moiety into more complex molecular architectures via etherification, esterification, or oxidation reactions.

Basic Information

Product Name	2,4-Bis(Trifluoromethyl)Benzyl Alcohol
CAS No.	143158-15-0
Molecular Formula	C10H6F6O
Molecular Weight	256.15 g/mol
Synonyms	2,4-Bis(trifluoromethyl)benzenemethanol; α,2,4-Bis(trifluoromethyl)benzenemethanol; (2,4-Bis(trifluoromethyl)phenyl)methanol; 2,4-Bis(trifluoromethyl)benzyl alcohol; 1-Hydroxymethyl-2,4-bis(trifluoromethyl)benzene; Benzyl alcohol, 2,4-bis(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,4-Bis(Trifluoromethyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.