Description

1-Hydroxyethyl-2'-Deoxyadenosine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard for studying nucleic acid chemistry, enzyme interactions, and metabolic pathways. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in the development of novel therapeutics and molecular probes.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate polymerase and kinase activities.
• Diagnostic Reagent Manufacturing: Serves as a critical component in the synthesis of probes and primers for molecular diagnostics and sequencing.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in laboratories.
• Life Science Research: Employed in studies related to DNA repair mechanisms, epigenetics, and cellular metabolism.

Basic Information

Product Name	1-Hydroxyethyl-2'-Deoxyadenosine
CAS No.	142997-59-9
Molecular Formula	C₁₂H₁₇N₅O₄
Molecular Weight	295.29 g/mol
Synonyms	1-(2-Hydroxyethyl)-2'-deoxyadenosine; 1-HE-dA; N1-(2-Hydroxyethyl)-2'-deoxyadenosine; 2'-Deoxy-N1-(2-hydroxyethyl)adenosine; 1-(2-Hydroxyethyl)deoxyadenosine; 1-HEA-dR; dA(1-HE)
EINECS	Contact for details

Quality Control

Our 1-Hydroxyethyl-2'-Deoxyadenosine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.