Description

3-Pyridinemethanol, 2-Chloro-α-((2-(Dimethylamino)Ethoxy)Methyl)-5-Fluoro-6-(Methylamino)-, Monohydrochloride is a high-purity, complex heterocyclic building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for its role in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex substituted pyridine core.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a precursor in multi-step synthetic routes for advanced, high-value APIs.
• Biochemical Tool Compound: Potential use in developing pharmacological probes for studying specific enzyme or receptor interactions.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	3-Pyridinemethanol, 2-Chloro-α-((2-(Dimethylamino)Ethoxy)Methyl)-5-Fluoro-6-(Methylamino)-, Monohydrochloride
CAS No.	142934-88-1
Molecular Formula	C12H19ClFN3O2 • HCl
Molecular Weight	320.21 g/mol (Free base: 283.75 g/mol)
Synonyms	2-Chloro-α-((2-(dimethylamino)ethoxy)methyl)-5-fluoro-6-(methylamino)-3-pyridinemethanol monohydrochloride; 5-Fluoro-6-(methylamino)-2-chloro-α-((2-(dimethylamino)ethoxy)methyl)-3-pyridinemethanol hydrochloride; L-689,560; L689560; L 689560; (RS)-2-Chloro-5-fluoro-6-(methylamino)-α-((2-(dimethylamino)ethoxy)methyl)nicotinyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanol derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, assay, and impurity profiles. We support compliance with ICH guidelines for stability and impurity characterization.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 97.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.