Description

6-o-Carboxymethylchitin-5-Fluorouracil is a chemically modified biopolymer conjugate designed for targeted drug delivery. This compound combines the biocompatibility and biodegradability of chitin derivatives with the potent chemotherapeutic activity of 5-fluorouracil. It is engineered to enhance therapeutic efficacy while minimizing systemic side effects. This advanced material is primarily targeted at the pharmaceutical research and development sector for creating novel, controlled-release anticancer formulations.

Application

• Targeted Anticancer Drug Delivery Systems: As a prodrug or carrier for the site-specific release of 5-fluorouracil in oncology treatments.
• Biomedical Hydrogels and Implants: Used in the formulation of injectable or implantable matrices for sustained local chemotherapy.
• Polymeric Nanoparticle Synthesis: Serves as a functional building block for creating nanoparticles with enhanced tumor accumulation.
• Wound Healing and Tissue Engineering: Potential application in medicated scaffolds where controlled release of an anticancer agent is needed post-surgical resection.
• Research and Development: A key intermediate for academic and industrial R&D focused on novel polymer-drug conjugates and smart biomaterials.

Basic Information

Product Name	6-o-Carboxymethylchitin-5-Fluorouracil
CAS No.	142870-69-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-FU-Carboxymethylchitin Conjugate; CM-Chitin-5-FU; 5-Fluorouracil-Carboxymethylchitosan Derivative; 6-O-Carboxymethylchitin Conjugated with 5-Fluorouracil; Anticancer Chitin Derivative; Polymeric Prodrug of 5-Fluorouracil; Biopolymer-5-FU Conjugate; N-Carboxymethylchitosan-5-Fluorouracil (related compound)
EINECS	Contact for details

Quality Control

Our 6-o-Carboxymethylchitin-5-Fluorouracil is produced under strict quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for research and development purposes. We provide comprehensive analytical data including HPLC for drug content, spectroscopic identification (FT-IR, NMR), and determination of the degree of substitution. A Certificate of Analysis (COA) detailing all specifications is available with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant to maintain integrity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (5-FU Content)	≥ 95.0% (by HPLC)
Degree of Substitution (DS)	Contact for details
Moisture Content	≤ 5.0% (Karl Fischer)
Solubility	Soluble in aqueous buffers, partially soluble in DMSO
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.