Description

Diethyl (2-Iodoethyl)Phosphonate is a versatile organophosphorus building block characterized by its reactive iodoethyl and phosphonate ester functionalities. This compound is essential for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research, where it serves as a key intermediate for carbon-carbon and carbon-phosphorus bond formation. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life sciences industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing phosphonate or phosphate ester groups.
• Agrochemical Synthesis: Used in the development of herbicides, insecticides, and plant growth regulators that leverage phosphonate chemistry.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphonate-based ligands for metal catalysis.
• Material Science Research: Employed in the creation of functionalized polymers and surface-modifying agents.
• Cross-Coupling Reactions: Acts as an alkylating agent or electrophile in various palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Useful for incorporating phosphonate motifs into biomolecules for studying enzyme mechanisms.

Basic Information

Product Name	Diethyl (2-Iodoethyl)Phosphonate
CAS No.	142778-06-1
Molecular Formula	C6H14IO3P
Molecular Weight	292.05 g/mol
Synonyms	(2-Iodoethyl)phosphonic Acid Diethyl Ester; Diethyl 2-Iodoethylphosphonate; Diethyl (2-Iodoethyl)Phosphonate; 2-Iodoethylphosphonic Acid Diethyl Ester; Ethyl (2-Iodoethyl)Phosphonate; (Iodoethyl)Diethyl Phosphonate; Diethyl Iodoethylphosphonate; Phosphonic Acid, (2-Iodoethyl)-, Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl (2-Iodoethyl)Phosphonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.