Description

B-L-Fucopyranosylphenyl Isothiocyanate is a specialized glycosyl isothiocyanate derivative, a crucial building block in carbohydrate chemistry and glycobiology research. This compound is essential for the chemoselective conjugation of fucose moieties to biomolecules, enabling the synthesis of complex glycoconjugates and probes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for applications such as glycan array fabrication, antibody-drug conjugate development, and the study of fucose-mediated biological recognition events.

Application

• Glycoconjugate Synthesis: A key reagent for the chemoselective labeling and conjugation of proteins, peptides, and other biomolecules with fucose residues.
• Glycan Array Fabrication: Used to immobilize fucose-containing oligosaccharides onto solid surfaces for high-throughput screening of carbohydrate-protein interactions.
• Diagnostic Probe Development: Enables the creation of fluorescent or affinity-tagged probes for detecting fucose-binding lectins and antibodies in assays.
• Pharmaceutical Research: Serves as a critical intermediate in the development of novel antibody-drug conjugates (ADCs) and targeted therapeutics that exploit fucose-specific pathways.
• Enzyme Substrate & Inhibitor Design: Acts as a scaffold for developing substrates or inhibitors for fucosyltransferases and other glycosylation-related enzymes.
• Material Science: Can be used to functionalize surfaces and nanomaterials with biologically active fucose ligands for biosensor and tissue engineering applications.

Basic Information

Product Name	B-L-Fucopyranosylphenyl Isothiocyanate
CAS No.	142702-33-8
Molecular Formula	C₁₃H₁₅NO₅S
Molecular Weight	297.33 g/mol
Synonyms	Phenyl 6-deoxy-β-L-galactopyranosyl isothiocyanate; β-L-Fucopyranosyl phenyl isothiocyanate; 1-Isothiocyanato-1-phenyl-β-L-fucopyranoside; Phenyl β-L-fucopyranoside isothiocyanate; 6-Deoxy-β-L-galactopyranosyl phenyl isothiocyanate; Phenyl 6-deoxy-β-L-galactoside isothiocyanate; β-L-Fucopyranosylphenyl ITC
EINECS	Contact for details

Quality Control

Our B-L-Fucopyranosylphenyl Isothiocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to quality assurance guarantees material integrity and reliable performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.