Description

2-Imidazoledistamycin is a specialized synthetic compound belonging to the distamycin family, known for its unique imidazole-modified structure. This modification is significant as it can enhance DNA-binding affinity and specificity, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery of novel antimicrobial, antiviral, and anticancer agents, as well as in the study of gene regulation and molecular biology.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents targeting DNA.
• Antimicrobial Research: Used in the development of new compounds with potential activity against bacteria and fungi.
• Antiviral Agent Development: Investigated for creating molecules that inhibit viral replication by interacting with viral DNA.
• Oncology Research: Employed in the design and study of potential anticancer drugs that function as DNA minor groove binders.
• Biochemical Tool: Utilized as a probe in molecular biology to study protein-DNA interactions and gene expression mechanisms.
• Academic & Contract Research: A critical reagent for universities and CROs conducting fundamental research in medicinal chemistry and biochemistry.

Basic Information

Product Name	2-Imidazoledistamycin
CAS No.	142211-78-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-Imidazoledistamycin; Distamycin A imidazole derivative; Imidazole-distamycin conjugate; 2-Imidazole-substituted distamycin; 2-Imidazolyl-distamycin; DNA minor groove binder with imidazole; (S)-N1-(3-((2-Amino-9H-purin-6-yl)amino)propyl)-N5-(1H-imidazol-2-yl)pentanediamide (theoretical IUPAC); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our 2-Imidazoledistamycin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.