Description

1-Oxaspiro[4.4]Nonane-4-Carbonyl Chloride, 2-Oxo- (9Ci) is a high-value, reactive spirocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its ability to introduce the 1-oxaspiro[4.4]nonane scaffold and a reactive carbonyl chloride group, enabling the construction of complex molecular architectures with high precision. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel small-molecule drugs, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific spirocyclic activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Employed in the synthesis of complex chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create activity-based probes (ABPs) or labeled compounds for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Oxaspiro[4.4]Nonane-4-Carbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	142183-70-8
Molecular Formula	C9H11ClO3
Molecular Weight	202.63 g/mol
Synonyms	2-Oxo-1-oxaspiro[4.4]nonane-4-carbonyl chloride; 1-Oxaspiro[4.4]nonane-4-carbonyl chloride, 2-oxo-; Spiro[4.4]nonane-4-carbonyl chloride, 1-oxa-2-oxo-; 2-Oxaspiro[4.4]nonane-4-carbonyl chloride (ambiguous); Tetrahydro-2H-spiro[furan-3,9'-xanthene]-4-carbonyl chloride, 2-oxo- (related structure); 4-(Chlorocarbonyl)-2-oxo-1-oxaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[4.4]Nonane-4-Carbonyl Chloride, 2-Oxo- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.