Description

2-(1-Hexyn-1-Yl)Adenosine-5'-Uronamide is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a potent and selective agonist for adenosine receptors, making it a critical intermediate in the development of novel therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for targeting cardiovascular, inflammatory, and neurological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel adenosine receptor-targeting drugs.
• Biochemical Research: Used as a high-affinity ligand in receptor binding assays and pharmacological studies to investigate adenosine signaling pathways.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity for therapeutic applications.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development and quality control of related compounds.
• Preclinical Development: Utilized in in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and metabolic profiles of candidate molecules.

Basic Information

Product Name	2-(1-Hexyn-1-Yl)Adenosine-5'-Uronamide
CAS No.	142103-07-9
Molecular Formula	C₁₇H₂₂N₆O₅
Molecular Weight	390.40 g/mol
Synonyms	2-(1-Hexyn-1-yl)adenosine-5'-uronamide; 2-Hex-1-yn-1-yladenosine-5'-carboxamide; 2-(Hex-1-yn-1-yl)adenosine-5'-carboxamide; 2-(1-Hexynyl)adenosine-5'-uronamide; 2-(1-Hexynyl)-N-(β-D-ribofuranosyl)adenine-5'-carboxamide; CVT-510; Tecadenoson (pharmaceutical development name); Adenosine A1 receptor agonist
EINECS	Contact for details

Quality Control

Our 2-(1-Hexyn-1-Yl)Adenosine-5'-Uronamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the material should be handled under anhydrous conditions or a dry inert atmosphere for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.