Description

13-cis-12-(3'-Carboxyphenyl)Retinoic Acid is a synthetic retinoid derivative of significant interest in advanced pharmaceutical research and development. This compound matters for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutics targeting specific nuclear receptors. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers focused on developing treatments in areas such as dermatology, oncology, and metabolic disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel retinoid-based drug candidates.
• Biochemical Research: Used as a reference standard or ligand in studies of retinoic acid receptor (RAR) and retinoid X receptor (RXR) pathways.
• Dermatological R&D: Investigated for potential applications in developing treatments for skin conditions like acne, psoriasis, and photoaging.
• Oncological Research: Explored for its role in cellular differentiation and proliferation studies relevant to cancer therapy.
• Metabolic Disorder Studies: Utilized in research targeting metabolic pathways influenced by retinoid signaling.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.

Basic Information

Product Name	13-cis-12-(3'-Carboxyphenyl)Retinoic Acid
CAS No.	141948-79-0
Molecular Formula	C24H26O4
Molecular Weight	378.46 g/mol
Synonyms	13-cis-12-(3-Carboxyphenyl)Retinoic Acid; 12-(3-Carboxyphenyl)-13-cis-retinoic Acid; 13-cis-12-(3'-Carboxyphenyl)Retinoate; (2Z,4E,6E,8E)-9-(3-Carboxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic Acid; Retinoid Derivative CAS 141948-79-0; 13-cis-12-(m-Carboxyphenyl)Retinoic Acid
EINECS	Contact for details

Quality Control

Our 13-cis-12-(3'-Carboxyphenyl)Retinoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research-grade and potential GMP standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature of 15-25°C (59-77°F) to minimize oxidation and degradation. Keep the container in a dry, cool, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.