Description

3-Hydroxycholestan-6-Yl Sulfate is a high-purity sterol sulfate derivative of significant interest in advanced biochemical research and development. This compound serves as a critical reference standard and synthetic intermediate for investigating sterol metabolism, signaling pathways, and membrane biology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on developing novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research Standard: Used as a high-purity reference material in analytical laboratories for method development and validation in sterol analysis.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex steroid-based drug candidates and bioactive molecules.
• Metabolic Pathway Studies: Employed in research to elucidate the role of sulfated sterols in cellular signaling, enzyme regulation, and metabolic disorders.
• Lipidomics & Proteomics: Acts as a standard or probe in mass spectrometry-based lipidomic studies to identify and quantify sterol sulfates in biological samples.
• Enzyme Substrate/Inhibitor: Utilized in enzymatic assays to study the activity of sulfotransferases or sulfatases involved in sterol modification.
• Cell Biology & Membrane Studies: Applied in research exploring the effects of sulfated sterols on membrane fluidity, receptor function, and cell communication.

Basic Information

Product Name	3-Hydroxycholestan-6-Yl Sulfate
CAS No.	141677-59-0
Molecular Formula	C27H48O5S
Molecular Weight	484.73 g/mol
Synonyms	Cholestan-6-ol, 3-hydroxy-, sulfate; 3-Hydroxycholestan-6-yl hydrogen sulfate; 6-Sulfooxy-3-hydroxycholestane; Sterol sulfate derivative; 3β,6α-Dihydroxycholestane 6-sulfate
EINECS	Contact for details

Quality Control

Every batch of 3-Hydroxycholestan-6-Yl Sulfate is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for all critical parameters including assay, purity, and identification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.