Description

6-Hydroxycholestan-3-Yl Sulfate is a sterol sulfate derivative, a key intermediate in the study of bile acid metabolism and steroid biochemistry. This compound matters for its role as a reference standard and a crucial building block in pharmaceutical research and development, enabling precise metabolic pathway analysis. It is primarily needed by research institutions, pharmaceutical companies, and diagnostic manufacturers focused on lipid metabolism, liver function studies, and the synthesis of novel therapeutic agents.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in the study of bile acid synthesis and cholesterol metabolism pathways.
• Pharmaceutical Development: Serves as a key starting material or intermediate for the synthesis of novel steroid-based therapeutics and diagnostic agents.
• Metabolite Analysis: Employed as an analytical standard in LC-MS and HPLC methods for the quantification of sterol sulfates in biological samples.
• Enzyme Activity Assays: Utilized as a substrate in assays to study the activity of sulfotransferases and other enzymes involved in steroid modification.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of calibrators and controls for diagnostic tests related to liver function and metabolic disorders.

Basic Information

Product Name	6-Hydroxycholestan-3-Yl Sulfate
CAS No.	141677-55-6
Molecular Formula	C₂₇H₄₈O₅S
Molecular Weight	484.73 g/mol
Synonyms	Cholestan-6-ol, 3-(sulfooxy)-, (3β,5α,6β)-; 6β-Hydroxycholestan-3β-yl sulfate; 3β-Sulfooxy-5α-cholestan-6β-ol; (3β,5α,6β)-3-(Sulfooxy)cholestan-6-ol; 5α-Cholestane-3β,6β-diol 3-Sulfate; 6-Hydroxycholestanyl Sulfate
EINECS	Contact for details

Quality Control

Our 6-Hydroxycholestan-3-Yl Sulfate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.