Description

3-Azi-1-((2-Acetamido-2-Deoxy-1-Galactopyranosyl)Thio)Butane is a specialized biochemical building block featuring a unique azide functional group linked to a galactosamine-derived thioether moiety. This compound is engineered for advanced applications in bioconjugation and chemical biology, where its reactive azide enables highly selective "click chemistry" reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors for the development of targeted probes, glycoconjugate vaccines, and novel drug delivery systems.

Application

• Bioconjugation Reagent: Used for site-specific labeling of proteins, antibodies, and oligonucleotides via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
• Glycobiology Research: Serves as a key intermediate for synthesizing neoglycoconjugates and studying carbohydrate-protein interactions.
• Diagnostic Probe Development: Enables the creation of fluorescent or affinity-tagged probes for cellular imaging and detection assays.
• Pharmaceutical Synthesis: Acts as a versatile linker in the development of antibody-drug conjugates (ADCs) and targeted therapeutics.
• Material Science Functionalization: Used to modify surfaces (e.g., nanoparticles, polymers) with bioactive carbohydrate motifs.
• Chemical Biology Tool: Facilitates activity-based protein profiling (ABPP) and other proteomic discovery platforms.

Basic Information

Product Name	3-Azi-1-((2-Acetamido-2-Deoxy-1-Galactopyranosyl)Thio)Butane
CAS No.	141411-40-7
Molecular Formula	C12H21N5O5S
Molecular Weight	347.39 g/mol
Synonyms	3-Azido-1-((2-acetamido-2-deoxy-β-D-galactopyranosyl)thio)butane; 1-Thio-β-D-galactopyranoside, 2-acetamido-2-deoxy-, 1-[3-azidobutyl]; Azido-functionalized GalNAc thioether; N-Acetylgalactosamine azide derivative; GalNAc-S-Azide; Click chemistry galactosamine reagent; Azidobutyl GalNAc thioether; 3-Azidobutyl 2-acetamido-2-deoxy-1-thio-β-D-galactopyranoside
EINECS	Contact for details

Quality Control

Our 3-Azi-1-((2-Acetamido-2-Deoxy-1-Galactopyranosyl)Thio)Butane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.