Description

2-(3-Cyclopentyl-1-Propyn-1-Yl)Adenosine is a chemically modified nucleoside analog, specifically engineered for advanced research and development applications. This compound is valued for its role as a potent and selective ligand in studying adenosine receptor signaling pathways, offering critical insights for therapeutic discovery. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on cardiovascular, neurological, and inflammatory disease models.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel adenosine receptor (A1, A2A, A2B, A3) agonists/antagonists.
• Biochemical Assay Development: Used in high-throughput screening (HTS) and binding assays to characterize receptor affinity and selectivity profiles.
• Preclinical Studies: Employed in in vitro and in vivo models to investigate cardioprotective, neuroprotective, and anti-inflammatory mechanisms.
• Chemical Biology Probes: Acts as a molecular tool for studying G-protein coupled receptor (GPCR) signaling cascades and downstream effects.
• Academic Research: Utilized in university laboratories for fundamental research on purinergic signaling and its physiological implications.
• Reference Standard Manufacturing: Supplied to analytical and quality control laboratories for method validation and compound identification.

Basic Information

Product Name	2-(3-Cyclopentyl-1-Propyn-1-Yl)Adenosine
CAS No.	141345-10-0
Molecular Formula	C18H23N5O4
Molecular Weight	373.41 g/mol
Synonyms	2-(3-Cyclopentylprop-1-yn-1-yl)adenosine; 2-(3-Cyclopentyl-1-propynyl)adenosine; Adenosine, 2-(3-cyclopentyl-1-propyn-1-yl)-; 2-Cyclopentylpropynyladenosine; CPA; 2-CPA; A2A Adenosine Receptor Ligand; Research Compound 141345-10-0
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Cyclopentyl-1-Propyn-1-Yl)Adenosine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and chromatographic data is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.