Description

Terazosin Hydrochloride is a high-purity pharmaceutical active ingredient, a selective α-1 adrenergic receptor antagonist. It is critical for the formulation of medications used to manage hypertension and benign prostatic hyperplasia (BPH). This compound is essential for pharmaceutical manufacturers and research institutions developing and producing effective therapeutic agents. We supply CAS NO 141269-45-6 to the global market with a focus on quality, consistency, and regulatory compliance.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of finished dosage forms for the treatment of hypertension.
• BPH Treatment Formulations: Key component in medications designed to alleviate symptoms of benign prostatic hyperplasia.
• Clinical Research & Development: Serves as a reference standard and raw material in preclinical and clinical studies for cardiovascular and urological conditions.
• Generic Drug Manufacturing: Sourced by generic pharmaceutical companies for the production of cost-effective therapeutic equivalents.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for managing hypertension in animals.
• Analytical Reference Standard: Used in quality control laboratories for identity confirmation and assay development via HPLC and other chromatographic methods.

Basic Information

Product Name	Terazosin Hydrochloride
CAS No.	141269-45-6
Molecular Formula	C₁₉H₂₅N₅O₄ • HCl
Molecular Weight	423.90 g/mol
Synonyms	Terazosin HCl; Terazosin Monohydrochloride; Terazosin Hydrochloride Anhydrous; Terazosin Hydrochloride Dihydrate; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine Monohydrochloride; Hytrin (brand name); Heitrin; Vicard
EINECS	Contact for details

Quality Control

Our Terazosin Hydrochloride is manufactured and tested under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for pharmaceutical applications, with testing typically including identification, assay, related substances, residual solvents, and specific tests. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all test results against predefined specifications. We can support compliance requirements for various pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water (KF)	≤ 5.0% (or as per specific grade)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.