Description

Terazosin Hydrochloride is a high-purity pharmaceutical active ingredient, a selective α-1 adrenergic receptor antagonist. It is a critical intermediate and active pharmaceutical ingredient (API) for the formulation of antihypertensive and benign prostatic hyperplasia (BPH) medications. This compound is essential for pharmaceutical manufacturers and research institutions developing and producing cardiovascular and urological therapeutics. The product is supplied under stringent quality control to ensure batch-to-batch consistency and regulatory compliance.

Application

• Primary Active Pharmaceutical Ingredient (API) for antihypertensive drug formulations.
• Key component in the manufacture of medications for Benign Prostatic Hyperplasia (BPH).
• Reference standard for analytical method development and validation in quality control laboratories.
• Critical raw material for clinical trial material (CTM) and investigational new drug (IND) applications.
• Intermediate in advanced pharmaceutical synthesis and process development.
• Research chemical for pharmacological studies targeting α-adrenergic receptors.

Basic Information

Product Name	Terazosin Hydrochloride
CAS No.	141269-44-5
Molecular Formula	C19H28ClN5O4 • HCl
Molecular Weight	459.82 g/mol
Synonyms	Terazosin HCl; Terazosin Monohydrochloride; Terazosin Hydrochloride Dihydrate; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine Monohydrochloride Dihydrate; Hytrin (brand name); Heitrin; Vicard; 2-[4-(Tetrahydrofuran-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine hydrochloride
EINECS	Contact for details

Quality Control

Our Terazosin Hydrochloride is manufactured and tested to meet the highest standards of purity and consistency. Production adheres to current Good Manufacturing Practices (cGMP) guidelines, and the material is suitable for use in regulated pharmaceutical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We ensure compliance with major pharmacopeial standards, including USP and EP, where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 8.0%
Related Substances (HPLC)	Total impurities: NMT 2.0% Any individual impurity: NMT 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	NMT 20 ppm
Sulfated Ash	NMT 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.