Description

(2E)-3-(3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride is a high-value organic intermediate characterized by its reactive acid chloride functional group and dimethoxy-substituted aromatic ring. This compound is critical for introducing the cinnamoyl moiety into target molecules, enabling the synthesis of more complex structures with specific electronic and steric properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cinnamic acid derivative structure can contribute to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating conjugated organic molecules used in electronic displays and lighting.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Friedel-Crafts acylation, amidation, and esterification reactions to create novel compounds.
• Flavor & Fragrance Ingredient Synthesis: Utilized in the controlled synthesis of complex aromatic esters and amides for high-value sensory products.

Basic Information

Product Name	(2E)-3-(3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride
CAS No.	141236-46-6
Molecular Formula	C11H11ClO3
Molecular Weight	226.66 g/mol
Synonyms	3,4-Dimethoxycinnamoyl Chloride; (E)-3,4-Dimethoxycinnamoyl Chloride; (2E)-3-(3,4-Dimethoxyphenyl)acryloyl Chloride; Cinnamoyl Chloride, 3,4-dimethoxy-; 3-(3,4-Dimethoxyphenyl)-2-propenoyl Chloride; (E)-3-(3,4-Dimethoxyphenyl)acryloyl Chloride; 141236-46-6; 3,4-Dimethoxy-trans-cinnamoyl Chloride
EINECS	Contact for details

Quality Control

Our (2E)-3-(3,4-Dimethoxyphenyl)Prop-2-Enoyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.